Liver

Specialisms
Title
Alcoholic Liver Disease
Cirrhosis & Consequences
Drug-Induced Liver Injury
Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Invasive Markers
Viral Hepatitis
Grants View all Grants
Title Amount
Fighting the Fatty Liver Pandemic £248,321
Translational Safety Biomarker Pipeline €28M
Functional characteristics of a rare MTTP mutation £9,850
Validation of the Genedrive for HCV RNA testing £53,576.00
Non-invasive detection, stratification and treatment of chronic liver disease in vulnerable elderly £134,746
Nottingham Molecular Pathology Node (NMPN) £2,400,000
Drug-Induced Liver Injury £78,327
Apply and Develop MRI techniques to characterize the changes in the small bowel associated with perm £10,000
Real world outcomes of treatment of HCV-infected patients based on the use of sofosbuvir £116,000
EASL registry Grant £35,798.33
Dietary evaluation and interventions in NAFLD in south indian community £9,904
Evaluation of Interventions designed to increase diagnosis and treatment of patients with HCV infect £1,112,000
Quantitative Magnetic Resonance Imaging (MRI) Techniques in the evaluation and estimation of portal £21,600
Scarred Liver Project £491,000
Pump Priming study £10,000
CIC Assessing chronic liver injury using dynamic MRI £69,597
Stratified Medicine to optimise Treatment for HCV infection £5,200,000
Focus groups NAFLD patients £10,110
Telomere Length and Telomerase Activity £8,260
The Assessment of Liver Fibrogenesis £61,983
Publications View all Publications
Title
Natural History of Histologically-proven Alcohol Related Liver Disease: A systematic review
Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions
Cohort profile: the Trivandrum non-alcoholic fatty liver disease (NAFLD) cohort
Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Allel
ACG Clinical Guideline for Alcoholic Liver Disease: The MELD Threshold for Corticosteroid Treatment
Multi organ assessment of Compensated Cirrhosis Patients using quantitative Magnetic Resonance Imagi
Pretreatment Lesions on Magnetic Resonance Imaging in Patients With Hepatitis C Virus Infection Diag
Pharmacogenomics of drug-induced liver injury (DILI): Molecular biology to clinical applications
A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis
Telomere, telomerase and liver disease
A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitr
Comorbidities and medications of patients with chronic hepatitis C under specialist care in the UK
Characteristics of liver transplant candidates delisted following recompensation and predictors of s
Clinical and microbiological features of infection in alcoholic hepatitis: an international cohort s
Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank
Effects of short-term energy restriction on liver lipid content and inflammatory status in severely
Economic evaluation of a community-based diagnostic pathway to stratify adults for non-alcoholic fat
Liver Transplantation is a Preferable Alternative to Palliative Therapy for Selected Patients with A
New metrics for the Lancet Standing Commission on Liver Disease in the UK
Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active dem
Risk of hepatocellular carcinoma among individuals with different aetiologies of cirrhosis: a popula
In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and
Prevalence of clinically significant liver disease within the general population, as defined by non-
Drug-induced liver injury: recent advances in diagnosis and risk assessment
Liver Transplantation is a Preferable Alternative to Palliative Therapy for Selected Patients with A
Increased liver fat and glycogen stores after consumption of high versus low glycaemic index food: A
Visual morphometry and three non-invasive markers in the evaluation of liver fibrosis in chronic liv
The effectiveness of daclatasvir based therapy in European patients with chronic hepatitis C and adv
Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and O
Non-invasive assessment of portal hypertension using quantitative magnetic resonance imaging
The detection of oesophageal varices using a novel, disposable, probe-based transnasal endoscope: a
Non-invasive assessment of portal hypertension using quantitative magnetic resonance imaging
Prevention of progression to cirrhosis in hepatitis C with fibrosis: effectiveness and cost effectiv
Outcomes after successful direct-acting antiviral therapy for patients with chronic hepatitis C and
Visual morphometry and three non-invasive markers in the evaluation of liver fibrosis in chronic liv
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis
Novel functional hepatitis C virus glycoprotein isolates identified using an optimized viral pseudot
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis
Flexible and rapid construction of viral chimeras applied to hepatitis C virus
Hepatitis C - Assessment to Treatment Trial (HepCATT) in primary care: study protocol for a cluster
Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease pheno
Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cir
Monozygotic twins with NASH cirrhosis: cumulative effect of multiple single nucleotide polymorphisms
Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 c
Clinically significant chronic liver disease in people with Type 2 diabetes: the Edinburgh Type 2 Di
Liver-related outcomes in a large cohort of patients with Type 2 diabetes on insulin or sulphonylure
Monozygotic twins with NASH cirrhosis: cumulative effect of multiple single nucleotide polymorphism
Reduced healthcare utilization following successful hepatitis C virus treatment in HIV-co-infected p
FibroGENE: A gene-based model for staging liver fibrosis
Novel human anti-claudin 1 mAbs inhibit hepatitis C virus infection and may synergize with anti-SRB1
Genome-Wide Association Studies in Drug-Induced Liver Injury: Step Change in Understanding the Patho
Multiplex Protein Analysis to Determine Fibrosis Stage and Progression in Patients With Chronic Hepa
The hepatitis C revolution part 2: difficult-to-treat groups and experimental approaches. Current op
Clinically significant chronic liver disease in people with Type 2 diabetes: the Edinburgh Type 2 Di
Human lectins and their roles in viral infections
Interferon-lambda rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver diseas
Chronic hepatitis C - what do the new drugs offer and who should get them first?
Human leukocyte antigen genetic risk factors of drug-induced liver toxicology
Incidence of Post-ERCP Pancreatitis From Direct Pancreatic Juice Collection in Hereditary Pancreatit
BDNF Val66Met and reward-related brain function in adolescents: Role for early alcohol consumption
gamma-Glutamyltransferase, but not markers of hepatic fibrosis, is associated with cardiovascular di
In silico and in vitro interrogation of a widely used HEV RT-qPCR assay for detection of the species
Metabolic phenotyping for enhanced mechanistic stratification of chronic hepatitis C-induced liver f
The evaluation of portal hypertension using quantitative magnetic resonance imaging (MRI)
Assessing the Spatial Precision of SE and GE-BOLD Contrast at 7 Tesla
Interferon-lambda rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disea
Steroids or Pentoxifylline for Alcoholic Hepatitis: Results of the STOPAH Trial
Type I Interferon Rapidly Restricts Infectious Hepatitis C Virus Particle Genesis
Non-invasive monitoring of liver fibrosis
The association of exposure to hepatitis B and C viruses with lung function and respiratory disease:
Separate and combined effects of 21-day bed rest and hypoxic confinement on body composition
Addressing liver disease in the UK: a blueprint for attaining excellence in health care and reducing
Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistan
Reasons for nonuse of antiviral treatment in patients with chronic hepatitis C infection and thrombo
Safety Comparison of 12-And 24-Week Treatments in HCV Genotype 1-Infected Patients With Cirrhosis: R
End-stage methotrexate-related liver disease is rare and associated with features of the metabolic s
Lack of Efficacy of an Inhibitor of PDE4 in Phase 1 and 2 Trials of Patients With Nonalcoholic Steat
Non-invasive hepatic biomarkers (ELF and CK18) in people with type 2 diabetes: the Edinburgh type 2
Lymphoepithelial cyst of the pancreas and elevated cyst fluid carcinoembryonic antigen: a diagnostic
A Mathematical Model of the Human Metabolic System and Metabolic Flexibility
N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury
Critical review of the prognostic significance of pathological variables in patients undergoing rese
Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl
Prediction of liver disease in patients whose liver function tests have been checked in primary care
Modelling the impact of improving screening and treatment of chronic hepatitis C virus infection on
Exercise training during normobaric hypoxic confinement does not alter hormonal appetite regulation
Serum Autoantibody Measurement for the Detection of Hepatocellular Carcinoma
Colicin import into E. coli cells: A model system for insights into the import mechanisms of bacteri
Gastrointestinal: Bouveret’s syndrome
Treatment of metastatic spinal lesions with a navigational bipolar radiofrequency ablation device: a
Prevalence and Natural History of Histologically Proven Chronic Liver Disease in a Longitudinal Coho
Effect of fructose and sucralose on flow-mediated vasodilatation in healthy, white European males
TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver
Genetic Basis of Drug-Induced Liver Injury: Present and Future
Dietary strategies for the management of cardiovascular risk: role of dietary carbohydrates
Extended duration therapy with pegylated interferon and ribavirin for patients with genotype 3 hepat
Effect of mixed meal challenge on liver fat content and serum markers of liver fibrosis-Does food de
Incidence and prevalence of cirrhosis in the United Kingdom, 1992-2001: A general population-based s
Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European liver f
People View all People
Photo Name Bio
guruprasad-aithal Professor Guruprasad Aithal Biography Professor Guruprasad P. Aithal is the Professor of Hepatology and the Head of the Division for the Nottingham Digestive Diseases Centre and Deputy Director of Nottingham Molecular Pathology Node. Professor Aithal is the GI & Liver Disorder…
Dr Aloysious Dominic Aravinthan
neil-guha Dr Neil Guha Dr Neil Guha is a Clinical Associate Professor in Hepatology at the University of Nottingham. He trained at Guy's and St. Thomas's hospitals and began his postgraduate career in hepatology at St. Mary's Hospital, London. His doctoral thesis, awarded by…
dr-jane-grove Dr Jane Grove I am an Assistant Professor in the Hepatology Group in the NIHR Nottingham Biomedical Research Centre and the MRC-funded Nottingham Molecular Pathology Node (http://www.nmpn.info/). My research includes translational research projects in the following…
Dr Naaventhan Palaniyappan
Dr Stuart Astbury I am a postdoctoral researcher working in the hepatology group within NDDC (Guru Aithal and Neil Guha). My current project is part of the MRC funded Nottingham Molecular Pathology Node, and aims to determine biomarkers of non alcoholic fatty liver disease…
Dr Edmond Atallah
Dr Jane Chalmers
tracey-wildsmith Tracey Wildsmith
Dr KB Leena Dr K B Leena has a doctoral Degree in Biochemistry from University of Kerala in 1997 and is an integral part of the Population health and Research Institute, Trivandrum. She is a co-investigator in many population based research initiatives such as a…
dr-steve-ryder Dr Stephen Ryder
Dr KT Shenoy Track Record in delivering research for the benefit of local economies and society: Implemented the Computerization of the Medical College and Hospital in Trivandrum in 2003-2004. Implemented the Telemedicine Unit for the Health Department in…
About the Nottingham Digestive Diseases Biomedical Research Centre
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