Professor John Scholefield

Professor John Scholefield

Queens Medical Centre Campus, Derby Road, Nottingham, NG7 2UH

+44 115 823 1149 View full bio
Professor of Surgery/ Consultant General and Colorectal Surgeon

Research Summary

Pharmacology of the anal sphincter, novel treatments for faecal incontinence and for anal fissures

Colorectal cancer screening

Molecular changes in early colorectal cancer

Radiotherapy in rectal cancer

Immunotherapy for colorectal cancer

Anal cancer and pre-malignant conditions


  • In vivo models for anal sphincter physiology
  • clinical trials in anorectal disease
  • Screening for colorectal cancer


  • Immunotherapy in treatment of patients with primary colorectal cancer
  • Sphincter pharmacology - (The Sir Jules Thorn Charitable Trust, Norgine, Help the Aged) (Norgine) (Help the Aged)
  • Follow up of the Nottingham Faecal Occult Blood Test Screening Cohort (Medical Research Council)
  • Research Fellowship investigating the mechanisms of symptomatic diverticular disease (with J. Simpson) (Medical Research Council and Royal College of Surgeons)
  • Health economics of colorectal cancer follow-up (Southern Derbyshire NHS Trust)