Professor John Atherton

Professor John Atherton

Queens Medical Centre Campus, Derby Road, Nottingham, NG7 2UH

+44 115 823 1034 View full bio
Pro-Vice Chancellor for the Faculty of Medicine & Health Sciences
Professor of Gastroenterology

John Atherton is Deputy Director of the Gastroenterology and Liver disorders theme within the NIHR Nottingham Biomedical Research Centre. He was the founding Director of the original NIHR Nottingham Digestive Diseases Biomedical Research Unit. John is also the Pro Vice Chancellor and Dean of the Faculty of Medicine and Health Sciences in the University of Nottingham. His main research interests are in the virulence of the stomach bacterium Helicobacter pylori, in the pathogenesis of peptic ulceration and gastric adenocarcinoma, and in the role of H. pylori in modulating other diseases. He supervises both laboratory and clinical research. He has held both MRC Clinician Scientist and Senior Fellowships and was awarded the Sir Francis Avery Jones Research Medal by the British Society of Gastroenterology.

John’s medical education was at Cambridge then Oxford University. After post-graduate training in medicine and gastroenterology, he trained in gastroenterology research with Professors Chris Hawkey and Robin Spiller in the UK, and in infectious disease research with Professors Martin Blaser and Timothy Cover in Vanderbilt University, USA. He settled in the University of Nottingham in 1995 and became a full Professor in 2001. In this role John continues to practice clinical gastroenterology as an NHS Consultant, through patient clinics and endoscopy lists, specialising in upper GI diseases. He teaches medical students and specialised masters students.

Outside Nottingham, John serves on the UK Medical Schools Council Executive as Treasurer. He is the Chairman of Midlands Health Innovation which co-ordinates activity, particularly industry and NHS liaison, between the research-intensive Midlands Universities. From 2013-2017 he was the Secretary-General of United European Gastroenterology, the body representing gastroenterologists and others interested in digestive diseases in Europe.

Functional association between the Helicobacter pylori virulence factors VacA and CagA
The Effect of the Human Gut-Signalling Hormone, Norepinephrine, on the Growth of the Gastric Pathoge
Comparative Metagenomic Study of Alterations to the Intestinal Microbiota and Risk of Nosocomial Clo
CCL20/CCR6-mediated migration of regulatory T cells to the Helicobacter pylori-infected human gastri
Does Helicobacter pylori protect against oesophageal adenocarcinoma, and if so, how?
Feasibility of reducing aspirin-associated ulcer bleeding by Helicobacter pylori eradication
Astrocytes are important mediators of A beta-induced neurotoxicity and tau phosphorylation in primar
Vacuolating Cytotoxin Genotypes Are Strong Markers of Gastric Cancer and Duodenal Ulcer-Associated H
The highly repetitive region of the helicobacter pylori CagY protein comprises tandem arrays of an a
A Population-Based Epidemiologic Study of Helicobacter Pylori Infection and its Association with Sys
Refining psychiatric phenotypes for response to treatment: Contribution of LPHN3 in ADHD
Assessment of the Mass Balance Recovery and Metabolite Profile of Avibactam in Humans and In Vitro D
Helicobacter pylori-induced acquired immunity and immunoregulation
A Novel Method for Genotyping the Helicobacter pylori vacA Intermediate Region Directly in Gastric B
The Pre-Test Risk Stratified Cost-Effectiveness of 64-Slice Computed Tomography Coronary Angiography
Reactive intermediates in the H-phosphonate synthesis of oligonucleotides
Expression of the H. pylori virulence factor vacuolating cytotoxin A (vacA) is influenced by a poten
Helicobacter pylori
Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric
The kinetics and mechanism of the acid-catalysed detritylation of nucleotides in non-aqueous solutio
Visualization of co-localization in A beta 42-administered neuroblastoma cells reveals lysosome dama
Helicobacter pylori Membrane Vesicles Stimulate Innate Pro- and Anti-Inflammatory Responses and Indu
Accurate quantification of H pylori density in human gastric biopsies using real-time PCR
The mechanism of the phosphoramidite synthesis of polynucteotides
Comparison of a point of care device against current laboratory methodology using citrated and EDTA
Effects of amino acids on skeletal muscle protein metabolism in young and older aged individuals: pa
Optimising the quantification of cytokines present at low concentrations in small human mucosal tiss
A study of age-specific Helicobacter pylori seropositivity rates in Iraq
Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43
Metals recycling maps and allocation procedures in life cycle assessment
Resistance exercise training reverses age-related impairments in macro and microvascular blood flow
Helicobacter pylori induces human dendritic cell maturation and duodenal ulcer promoting gene a (dup
The inflammatory and immune response to Helicobacter pylori infection
Peptic ulcer disease
Differences in Helicobacter pylori CagA tyrosine phosphorylation motif patterns between western and
Modelling the occurrence and severity of enoxaparin-induced bleeding and bruising events
Helicobacter pylori Stimulates Dendritic Cells To Induce Interleukin-17 Expression from CD4(+) T Lym
Reply to “Helicobacter pylori vacA as Marker for Gastric Cancer and Gastroduodenal Diseases: One but
Helicobacter pylori dupA Is Polymorphic, and Its Active Form Induces Proinflammatory Cytokine Secret
The Spectrum of Helicobacter-Mediated Diseases
Helicobacter pylori: the role of the immune response in pathogenesis
The Clinical Utility and Diagnostic Yield of Routine Gastric Biopsies in the Investigation of Iron D
3-Dimensional Patient-Derived Lung Cancer Assays Reveal Resistance to Standards-of-Care Promoted by
Helicobacter pylori vacA transcription is genetically-determined and stratifies the level of human g
A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori-Induced Metaplas
Gastritis, peptic ulceration and related conditions