Dr Luca Marciani

Dr Luca Marciani

Queens Medical Centre Campus, Derby Road, Nottingham, NG7 2UH

+44 115 823 1248 View full bio
Associate Professor in GI MRI

I graduated in Physics at the University of Genoa in Italy. I then worked in Milan and London before joining the University of Nottingham, where I was awarded my PhD in Physics. Following a series of multi-disciplinary research contracts and Fellowships (including a Wellcome Trust VIP Fellowship and a RCUK Academic Fellowship) held across the Sir Peter Mansfield Imaging Centre and the Nottingham Digestive Diseases Centre (NDDC) I am now Associate Professor in Gastrointestinal MRI in the NDDC.

My research focuses on gastrointestinal physiology and pathology using magnetic resonance imaging (MRI) methods in combination with other physiological and behavioural techniques. My personal expertise is in imaging the human gastrointestinal (GI) tract using MRI. I have a particular interest in in-body imaging of food materials and in the GI response to factors in foods. I work within a team that has developed a unique cross-disciplinary collaboration between gastroenterologists, surgeons, physiologists, MRI physicists, food scientists and industrial collaborators from the food and pharmaceutical industries in the UK and abroad.

I have published 61 research papers and 11 book chapters, I have been principal investigator and co-investigator on academic and commercial research grants worth £5.2 million, and I have been regular peer-reviewer for 2 MRI and 2 gastroenterology international journals and for the ISMRM international scientific meeting. I serve on the Nottingham Digestive Disease Biomedical Research Unit Strategy Board and on the University’s Human Research Scanners Management Committee. I was awarded the RinR/Wellcome/RCUK Communicator’s Award for my science outreach work with secondary school pupils.

Publications
Title
Characterization of the time course of the superior mesenteric, abdominal aorta, internal carotid an
The effects of loperamide, or loperamide plus simethicone, on the distribution of gut water as asses
A randomised trial of ondansetron for the treatmentof irritable bowel syndrome with diarrhoea
Additive effects of gastric volumes and macronutrient composition on the sensation of postprandial f
Investigating the effects of an oral fructose challenge on hepatic ATP reserves in healthy volunteer
Investigation of alginate gel inhomogeneity in simulated gastro-intestinal conditions using magnetic
Investigation of the behaviour of chitosan microparticles as pH responsive hydrogels in the gastro-i
A low calorie morning meal prevents the decline of hepatic glycogen stores: a pilot in vivo (13)C ma
Effects of bowel cleansing on the intestinal microbiota
Distinct Abnormalities of Small Bowel and Regional Colonic Volumes in Subtypes of Irritable Bowel Sy
Postprandial Changes in Small Bowel Water Content in Healthy Subjects and Patients With Irritable Bo
Cortical brain activation in anticipation of somatic pain in symptomatic diverticular disease
Magnetic resonance spectroscopy measurements ofintragastric fat fraction of oil emulsions in humans
Magnetic Resonance Imaging Methods for the Study of Gastrointestinal Transit
Colonic response to laxative ingestion as assessed by MRI differs in constipated irritable bowel syn
Effects of a 5-HT3 antagonist, ondansetron, on fasting and postprandial small bowel water content as
Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and
Investigating the effects of an oral fructose challenge on hepatic ATP reserves in healthy volunteer
The cortical response to the oral perception of fat emulsions and the effect of taster status
Delayed gastric emptying and reduced postprandial small bowel water content of equicaloric whole mea
Fasting and postprandial volumes of the undisturbed colon: normal values and changes in diarrhea-pre
The Effect of Body Position on Flavor Release and Perception: Implications for fMRI Studies
Use of an Immediate Swallow Protocol to Assess Taste and Aroma Integration in fMRI Studies
Stimulation of colonic motility by oral PEG electrolyte bowel preparation assessed by MRI: compariso
Whole body magnetic resonance imaging (MRI)
Assessment of gastrointestinal motor functions by MRI: a comprehensive review
Fasting and postprandial volumes of the undisturbed colon: normal values and changes in diarrhea-pre
Effect of bread gluten content on gastrointestinal function: a crossover MRI study on healthy humans
Corticotropin-releasing factor increases ascending colon volume after a fructose test meal in health
Effect of intragastric acid stability of fat emulsions on gastric emptying, plasma lipid profile and
Preventing Gastric Sieving by Blending a Solid/Water Meal Enhances Satiation in Healthy Humans
Effects of Bolus and Continuous Nasogastric Feeding on Gastric Emptying, Small Bowel Water Content,
Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI
Assessment of motion of colonic contents in the human colon using MRI tagging
Effects of Bolus and Continuous Nasogastric Feeding on Gastric Emptying, Small Bowel Water Content,
Investigating the effects of an Oral Fructose Challenge on Hepatic ATP Reserves in Healthy Volunteer
Cortical brain activation in response to somatic pain in symptomatic diverticular disease
Prior Consumption of a Fat Meal in Healthy Adults Modulates the Brain’s Response to Fat
Distinct Abnormalities of Small Bowel and Regional Colonic Volumes in Subtypes of Irritable Bowel Sy
Exploring gastrointestinal variables affecting drug and formulation behavior: Methodologies, challen
Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI
Gastric emptying of three liquid oral preoperative metabolic preconditioning regimens measured by ma
Magnetic resonance imaging to evaluate gastrointestinal function
Development and validation of a large, modular test meal with liquid and solid components for assess
Quantification of Gastrointestinal Liquid Volumes and DistributionFollowing a 240 mL Dose of Water i
Anticipation of thermal pain in diverticular disease
Magnetic resonance imaging to evaluate gastrointestinal function
Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-re
MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans
Increased liver fat and glycogen stores after consumption of high versus low glycaemic index food: A
Magnetic resonance imaging biomarkers of gastrointestinal motor function and fluid distribution