Utility of infrared fluorescence endoscopy in assessment of gastrointestinal inflammation and neoplasia: a pilot study (Infrared Study)

1st August 2010

Status: Ended

Specialism: Upper GI.

Team: Professor Krish Ragunath.

Gastroenterologists assess the lining of the intestines (like stomach and bowel) with a camera called an endoscope. White light from the camera light source is reflected from the lining and captured to obtain images of the lining. With theinfrared endoscope, in addition to white light an infrared mode is used where infrared light is shone on the lining after injecting a contrast agent called indocyanine green (used extensively and safely over the last 30 years to assess the heart and blood vessels in the eye) and the relfected light is captured to produce an image of the lining that enables better visualization of the deeper blood vessels under the lining of the intestines (called submucosal blood vessels). This will enable better assessment of inflammatory and cancerous changes in the lining of the intestines. This study will look at the utility of this new modality of endoscopy in assessing inflmmation and cancer in the lining of the intestines and compare it to histology.

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professor-krish-ragunath Professor Krish Ragunath Krish Ragunath is Professor of GI Endoscopy, Head of Endoscopy Service and Consultant Gastroenterologist at the Nottingham University Hospitals. He is the BSG International Secretary, Fellow of the Royal College of Physicians of Edinburgh and London. He…
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