Pro-Euro-DILI Registry: Creation of a multicentre and multidisciplinary European registry of prospective drug-induced liver injury cases
1st February 2016 - ongoing
Status: In Recruitment
Specialism: Liver, Drug-Induced Liver Injury.
- To set-up an international European registry of patients with idiosyncratic DILI, (iDILI) enrolled prospectively with the collation of in-depth phenotyping: including details of drug dose, duration, concomitant medications, host demography, comorbidity including insulin sensitivity as well as the course of the event.
- To enrol a similarly well-characterised control group of people who are exposed to medications matched for those implicated in DILI.
- To collect and store biological samples (blood, urine, stool and liver biopsy) from patients with idiosyncratic DILI through the course (at onset and follow-up) of the event.
|Professor Guruprasad Aithal||Professor Aithal has been a Consultant Hepatobiliary Physician at Nottingham University Hospitals NHS trust since 2001. He is the Head of the NIHR Nottingham Digestive Diseases Biomedical Research Centre, and the Head of Division for the Nottingham…|
|Dr Jane Grove||I am a research scientist in the Hepatology Group (Guru Aithal & Neil Guha) in the NIHR Nottingham Digestive Diseases Biomedical Research Unit. I am involved in translational research in the following areas: Drug-induced liver injury (assessment,…|