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Studies
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- MRI assessment of mode of action of Bisacodyl, single dose (MODS)
- The effects of an iso-energetic low glycemic index diet on liver fat accumulation and gut microbiota
- (GAME-COSMIC)
- A Mechanistic Investigation into Drug and Chemical Induced Hypersensitivity Reactions
- Small bowel permeability and associated changes of MRI measures in patients with liver cirrhosis
- IL-1 Signal Inhibition in Alcoholic Hepatitis
- Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS): Assessment & Validation of
- Feasibility studies to investigate the role of ursodeoxycholic acid in the prevention of recurrence
- The PRognostic effect of Environmental factors in Crohn’s and Colitis
- STopping Aminosalicylate Therapy in Inactive Crohn’s Disease (STATIC) Study: A Randomized, Open-labe
- The role of gut microbiome in chronic inflammatory diseases: developing tools for analysis of interv
- Fighting the fatty liver pandemic: Developing effective protocols & local expertise to deliver & eva
- The Impact of Type 2 Diabetes and Exercise on Liver Fat Quality
- Non-invasive approaches to identify the cause of fatigue in inflammatory bowel disease patients
- A randomized, double-blind, placebo-controlled, multicenter, dose-range, proof-of-concept, 24-week t
- Autologous Stem cell Transplantation In refractory Crohn’s disease – Low Intensity Therapy Evaluatio
- The effect of oral feeding on gastric emptying, small bowel water content, superior mesenteric arter
- A Phase 2a, Randomized, Partially-blind, Placebo-controlled Study to Assess the Efficacy, Safety, an
- Wide area transepithelial sample esophageal biopsy combined with computer assisted 3-dimensional tis
- Ondansetron for the treatment of IBS with diarrhoea: predicting the responder
- A two-part randomized, double-blind, placebo-controlled multicenter dose ranging and confirmatory st
- A feasibility study to measure gut transit in paediatric constipation using novel mini-capsules and
- Effect of Carnitine supplementation on Liver steatosis, Insulin sensitivity, Plasma glucose homeosta
- Effects of Fibre on Intestinal Volume and Gas in Irritable Bowel Syndrome (EFIGI)
- Barrett’s oESophagus Trial 3 (BEST3): Cluster randomised controlled trial comparing the Cytosponge
- A new MRI-based disease measure in Ulcerative Colitis – Optimisation studies in Healthy Volunteers
- Using non- contrast sequences to characterise and quantify the small bowel wall in healthy volunteer
- TRANqUIL trial
- The influence of ethnicity on non-alcoholic fatty liver disease in people of South Asian origin
- A cross-sectional study to assess the reliability of infrared thermography (IRT) in measuring brown
- Bioprospecting plant extracts (and marine biota) for anti-C. difficile potential
- A 24-week double blind treatment and 24-week follow up, randomized, multi-center, placebo-controlled
- A Long-Term Extension Study to Evaluate the Safety of Filgotinib in subjects with Ulcerative Colitis
- Combined Phase 2b/3. Double-Blind, Randomized, Placebo-Controlled Studies Evaluating the Efficacy an
- Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT)
- A Phase 2 double blinded, randomised, placebo controlled dose-finding study to evaluate the safety t
- Beta-blocker Stratification using quantitative MRI techniques to assess portal pressure and Response
- A Phase 2b, randomised, double blind, placebo controlled, parallel-group, multicentre protocol to ev
- A prospective randomized multicentre study comparing endoscopic pneumatic balloon dilation and per o
- Reclassifying Constipation Using Magnetic Resonance Imaging Combined With High Resolution Manometry:
- A new MR-based Perianal Crohn’s disease activity score: A multi-centre study (The MAP study)
- A Phase 3, long-term active treatment extension study of mongersen (GED-0301) in subjects with Crohn
- NASH meal response study: The Study of Genetic Factors Involved in Post-Prandial Fat Processing and
- A randomised double-blind controlled phase III study to compare the efficacy and safety of intraveno
- The effect of oral feeding on gastric emptying, small bowel water content, superior mesenteric arter
- A phase I, randomised, double-blind, placebo-controlled, multi-centre, ascending-dose trial to evalu
- A Phase 3, double blind, Randomised, Long-Term, Placebo Controlled, Multicentre study Evaluating the
- The accuracy and acceptability of magnet assisted capsule endoscopy in the diagnosis of oesophageal
- Characterisation of the structural changes associated with small bowel Permeability using MRI in Hea
- The accuracy and acceptibility of magnet assisted capsule endoscopy in the diagnosis of oesophageal
- Pro-Euro-DILI Registry: Creation of a multicentre and multidisciplinary European registry of prospec
- Effect of physical form of apples on gastrointestinal function and satiety: a MRI study (APPLE Study
- A Randomised, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of Topical Alicafors
- Muscle physiology & function in Crohn’s disease and non-alcoholic liver disease
- A pilot randomised controlled trial of the effect of a diet low in poorly digested carbohydrates on
- Case-control Study Evaluating the Genetic Factors Associated with the Development of Non-alcoholic S
- Poorly absorbed carbohydrates (PAC): A case control study between Irritable Bowel Syndrome patients
- A single arm, two-stage, multi-centre, phase II clinical trial investigating the safety and activity
- Assessing Nutrition Through Observation (ANTO Study)
- Evaluation of antibodies to tumor associated antigens as a diagnostic test for hepatocellular carcin
- Reduced intestinal motility in inflammatory Crohn’s Disease optimisation studies on healthy voluntee
- A pilot study to assess the efficancy of intravenous iron isomaltoside 1000 monofer in the managemen
- Magnetic resonance spectroscopy (MRS) Estimation of Glutathione flux in the Liver (MEGL)
- Eating behaviour in Crohn’s disease
- MRI assessment in newly diagnosed coeliac disease and following gluten-free diet treatment (MARCO)
- Reduced Intestinal Motility in Inflammatory Crohn’s Disease (MIC 2)
- Prognostic Biomarkers in HCV Cirrhosis
- Development of quantitative MRI measures for the preliminary assessment and characterization of the
- Optimisation of MRI for use with PEG Electrolyte Challenge Drink for stimulating and observing colon
- The GEM Project: A Multidisciplinary Study on the Genetic, Environmental and Microbial Interactions
- Nottingham Digestive Diseases Biomedical Research Unit Research Tissue Bank
- Exercise therapy to treat abnormalities in appetite and food intake in active Crohn’s disease (Exerc
- Randomised evaluation of algorithm for Crohn’s treatment - Study 2 (REACT 2)
- Altered appetite in Crohn’s disease: The role of the enteroendocrine axis (BROAD)
- A pilot study in healthy volunteers to assess the influence of time spent in the Trendelenburg posi
- Diagnosis of acid reflux disease using novel imaging: A prospective study (NBI NERD)
- A randomised controlled trial of the effect of the low FODMAP diet and dietary oligofructose on gast
- A pilot double blind, randomised, placebo controlled trial of the effect of a diet low in poorly dig
- Evaluation of interventions designed to increase diagnosis and treatment of patients with hepatitis
- Endoscopic trimodal imaging vs. chromoendoscopy as surveillance strategy for neoplasia in ulcerative
- Evaluation of the role of AST:ALT ratio, ELF markers and fibroscan in the detection of methotrexate
- HCV Research UK MRI Study
- Evaluation of the diagnostic accuracy of the Controlled Attenuation Parameter (CAP) measured by Fibr
- Validation of Magnetic Resonance Imaging to characterise gastrointestinal physiology, gut luminal co
- Assessment of a minimally invasive oesophageal cytology collection system (CE marked) in patients wi
- MRI and Microbiota Analysis in Constipation (MIMIC)
- High intensity training & insulin sensitivity: a tissue specific assessment
- The Effects of Isovolumetric and Isoeffective Infusions of Colloid Versus Crystalloid on Renal Blood
- Trent Study of patients with hepatitis C virus infection (HCV Trent Study)
- An investigation of the prevalence and dynamics of carriage of C. difficile in different IBD outpati
- Drug Induced Liver Injury Cohort in Nottingham (DILICIN)
- Functional Magnetic Resonance Imaging (MRI) in assessing dynamic changes induced by hypercapnia,hype
- An Observational Study of the Role of Antibiotics, Inflammation and Changes in Microbiota in the dev
- A double blind randomised placebo controlled phase III trial in patients with chronic idiopathic con
- A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety a
- A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety a
- A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety a
- The Evaluation of Portal Hypertension Using Quantitative Magnetic Resonance Imaging (MRQuee study
- The Evaluation of Portal Hypertension Using Quantitative Magnetic Resonance Imaging (MRQuee study
- A pivotal study to evaluate the efficacy of GFT505 80mg and GFT505 160mg on steatohepatitis in patie
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Publications
- Entries
- Allogeneic blood and postoperative cancer outcomes: correlation or causation?
- Response to Comment on: Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdomin
- Identification of Infectious Agents in High-Throughput Sequencing Data Sets Is Easily Achievable Usi
- Early Clinical Outcomes of a Rapid Colorectal Cancer Diagnosis Pathway using Faecal Immunochemical T
- Use of laparoscopic videos amongst surgical trainees in the United Kingdom
- The Impact of Preexisting and Post-transplant Diabetes Mellitus on Outcomes Following Liver Transpla
- Response to Comment on “Knight SR et al: The Impact of Preoperative Immune Modulating Nutrition on O
- Effect of flaxseed supplementation on lipid profile: An updated systematic review and dose-response
- Hyperosmolar dehydration: A predictor of kidney injury and outcome in hospitalised older adults
- Lower gut microbiome diversity and higher abundance of proinflammatory genus Collinsella are associa
- Efficacy of l-carnitine supplementation for management of blood lipids: A systematic review and dose
- Beneficial effects of l-carnitine supplementation for weight management in overweight and obese adul
- Glycaemic, gastrointestinal, hormonal and appetitive responses to pearl millet or oats porridge brea
- Prediction of Survival Among Patients Receiving Transarterial Chemoembolization for Hepatocellular C
- Effects of strawberry supplementation on cardiovascular risk factors: a comprehensive systematic rev
- Validation of the AASLD recommendations for classification of oesophageal varices in clinical practi
- Efficacy of direct-acting antivirals: UK real-world data from a well-characterised predominantly cir
- Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of Bifidobacterium long
- A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumet
- Long-Term Obeticholic Acid Therapy Improves Histological Endpoints in Patients With Primary Biliary
- Sofosbuvir/velpatasvir for 12weeks in hepatitis C virus-infected patients with end-stage renal disea
- Diagnosis of Barrett’s esophagus and esophageal varices using a magnetically assisted capsule endosc
- The risk of venous thromboembolism after surgery for esophagogastric malignancy and the impact of ch
- Effect of exercise intensity on circulating hepatokine concentrations in healthy men
- Editorial: understanding differences in patient response to ondansetron in irritable bowel syndrome
- Impact of IFNL4 Genetic Variants on Sustained Virologic Response and Viremia in Hepatitis C Virus Ge
- Outcomes Following an Index Emergency Admission With Cholecystitis: A National Cohort Study
- Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in human
- Gastrointestinal peptides and small-bowel hypomotility are possible causes for fasting and postprand
- Winter cancellations of elective surgical procedures in the UK: a questionnaire survey of patients o
- Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor subunit 3C polymorphism in irritabl
- First translational consensus on terminology and definitions of colonic motility in animals and huma
- The impact of reduced red and processed meat consumption on cardiovascular risk factors; an interven
- Interferon lambda 4 impacts the genetic diversity of hepatitis C virus
- Design and testing of microbubble-based MRI contrast agents for gastric pressure measurement
- How to select patients for antireflux surgery? The ICARUS guidelines (international consensus regard
- Obesity Is the Most Common Risk Factor for Chronic Liver Disease: Results From a Risk Stratification
- Treatment of irritable bowel syndrome with diarrhoea using titrated ondansetron (TRITON): study prot
- Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic
- Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No I
- Phosphorylation and functionality of CdtR in Clostridium difficile
- Publisher Correction: SOX9 regulated matrix proteins are increased in patients serum and correlate w
- Policosanol supplementation significantly improves blood pressure among adults: A systematic review
- Drug-induced liver injury
- The Impact of Preoperative Immune Modulating Nutrition on Outcomes in Patients Undergoing Surgery fo
- The Role of Oral Antibiotic Preparation in Elective Colorectal Surgery: A Meta-analysis
- Sexual Dimorphism of Brown Adipose Tissue Function
- Obesity in acute alcoholic hepatitis increases morbidity and mortality
- Meta-analysis of randomized clinical trials of early versus delayed cholecystectomy for mild gallsto
- Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug us
- The association between hepatocellular carcinoma and direct-acting anti-viral treatment in patients
- Follow-on RifAximin for the Prevention of recurrence following standard treatment of Infection with
- Free sugars
- Donor outcomes in anonymous live liver donation
- Editorial: Epigenetics in Mammalian Tissues
- Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with
- Drug Development for Nonalcoholic Fatty Liver Disease: Landscape and Challenges
- Changes in Testing for and Incidence of Celiac Disease in the United Kingdom: A Population-based Coh
- Defecatory urge increases cognitive control and intertemporal patience in healthy volunteers
- Lactoferrin-Loaded Alginate Microparticles to Target Clostridioides difficile Infection
- Efficacy of l-carnitine supplementation for management of blood lipids: A systematic review and dose
- Enteral versus parenteral nutrition following pancreaticoduodenectomy: a systematic review and meta-
- The Use of Prophylactic Somatostatin Therapy Following Pancreaticoduodenectomy: A Meta-analysis of
- Natural History of Histologically-proven Alcohol Related Liver Disease: A systematic review
- Of Potions, Poisons, Polygonum, and Pre-emptive Polymorphism
- Outcomes on the Use of Hemospray in Upper Gastrointestinal Bleeds Secondary to Tumours: Outcomes fro
- “Development of Fixed Dose Combination Products” Workshop Report: Considerations of Gastrointestina
- Comparison of Outcomes with Semi-mechanical and Circular Stapled Intrathoracic Esophagogastric Anast
- Caffeine exposure induces browning features in adipose tissue in vitro and in vivo
- Risk of infection associated with intravenous iron preparations: protocol for updating a systematic
- Effects of pro-/synbiotic supplementation on anthropometric and metabolic indices in overweight or o
- The Efficacy of Reverse Bevel Versus Franseen Needle in Acquiring Adequate Cytology in Gastrointesti
- Service evaluation of faecal immunochemical testing and anaemia for risk stratification in the 2-wee
- RiboCas: A Universal CRISPR-Based Editing Tool for Clostridium
- The mechanisms of pharmacokinetic food-drug interactions - A perspective from the UNGAP group
- Sofosbuvir/Velpatasvir for 12 Weeks in Hepatitis C Virus-Infected Patients with End-Stage Renal Dise
- Rectal area as surrogate measure of rectal emptying during MR defecography
- The impact of pre-operative intravenous iron on quality of life after colorectal cancer surgery: out
- Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based
- Phase enhanced PSIR T1 weighted imaging improves contrast resolution of the nucleus basalis of Meyne
- Outcomes on the Use of Hemospray in Gastrointestinal Bleeds Post Endoscopic Therapy: Outcomes from t
- Outcomes on the Use of Hemospray in Upper Gastrointestinal Bleeds Secondary to Peptic Ulcers: Prospe
- Follow-on RifAximin for the Prevention of recurrence following standard treatment of Infection with
- Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions
- Cohort profile: the Trivandrum non-alcoholic fatty liver disease (NAFLD) cohort
- Interferon-Induced Transmembrane Proteins Mediate Viral Evasion in Acute and Chronic Hepatitis C Vi
- Amino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sof
- Intraluminal Impact of Food: New Insights from MRI
- Enhancing our understanding of small bowel function using modern imaging techniques
- Carbohydrate-Dependent and Antimicrobial Peptide Defence Mechanisms Against Helicobacter pylori Infe
- A pilot study of visceral fat and its association with adipokines, stool calprotectin and symptoms i
- In search of stool donors: a multicenter study of prior knowledge, perceptions, motivators, and dete
- Magnetically assisted capsule endoscopy in suspected acute upper-GI bleeding versus esophagogastrodu
- Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom populati
- Interscapular and Perivascular Brown Adipose Tissue Respond Differently to a Short-Term High-Fat Di
- Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Popu
- Evolution of treatment targets in Crohn’s disease
- Mortality in people with coeliac disease: Long-term follow-up from a Scottish cohort
- Hybrid-biopsy endoscopic mucosal resection: an effective and simple technique for flat colorectal le
- Development and Validation of Confocal Endomicroscopy Diagnostic Criteria for Low-Grade Dysplasia in
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