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Studies
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- Evaluating Clinical, Endoscopic and Biomarker Variables in Assessment, Treatment and Outcome End poi
- Longitudinal Evaluation of Pt Outcomes & Impact Assessment on Family Members of Home Parenteral Nutr
- Effects of low glycemic index diet on hepatic lipids accumulation in relation to early life factors
- Ancillary study evaluating ChAd155-hIi-HBV shedding in a subset of chronic hepatitis B patients enro
- MRI assessment of mode of action of Bisacodyl, single dose (MODS)
- The NAFLD BioResource, part of the NIHR BioResource – A Research Study to Characterise Novel Clinica
- The Liverscreen Project: A population-based study to detect Liver fibrosis
- The effects of an iso-energetic low glycemic index diet on liver fat accumulation and gut microbiota
- (GAME-COSMIC)
- A Mechanistic Investigation into Drug and Chemical Induced Hypersensitivity Reactions
- Small bowel permeability and associated changes of MRI measures in patients with liver cirrhosis
- IL-1 Signal Inhibition in Alcoholic Hepatitis
- Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS): Assessment & Validation of
- Feasibility studies to investigate the role of ursodeoxycholic acid in the prevention of recurrence
- The PRognostic effect of Environmental factors in Crohn’s and Colitis
- STopping Aminosalicylate Therapy in Inactive Crohn’s Disease (STATIC) Study: A Randomized, Open-labe
- The role of gut microbiome in chronic inflammatory diseases: developing tools for analysis of interv
- Fighting the fatty liver pandemic: Developing effective protocols & local expertise to deliver & eva
- The Impact of Type 2 Diabetes and Exercise on Liver Fat Quality
- Non-invasive approaches to identify the cause of fatigue in inflammatory bowel disease patients
- A randomized, double-blind, placebo-controlled, multicenter, dose-range, proof-of-concept, 24-week t
- Autologous Stem cell Transplantation In refractory Crohn’s disease – Low Intensity Therapy Evaluatio
- The effect of oral feeding on gastric emptying, small bowel water content, superior mesenteric arter
- A Phase 2a, Randomized, Partially-blind, Placebo-controlled Study to Assess the Efficacy, Safety, an
- Wide area transepithelial sample esophageal biopsy combined with computer assisted 3-dimensional tis
- Ondansetron for the treatment of IBS with diarrhoea: predicting the responder
- A two-part randomized, double-blind, placebo-controlled multicenter dose ranging and confirmatory st
- A feasibility study to measure gut transit in paediatric constipation using novel mini-capsules and
- Effect of Carnitine supplementation on Liver steatosis, Insulin sensitivity, Plasma glucose homeosta
- Effects of Fibre on Intestinal Volume and Gas in Irritable Bowel Syndrome (EFIGI)
- Barrett’s oESophagus Trial 3 (BEST3): Cluster randomised controlled trial comparing the Cytosponge
- A new MRI-based disease measure in Ulcerative Colitis – Optimisation studies in Healthy Volunteers
- Using non- contrast sequences to characterise and quantify the small bowel wall in healthy volunteer
- TRANqUIL trial
- The influence of ethnicity on non-alcoholic fatty liver disease in people of South Asian origin
- A cross-sectional study to assess the reliability of infrared thermography (IRT) in measuring brown
- Bioprospecting plant extracts (and marine biota) for anti-C. difficile potential
- A 24-week double blind treatment and 24-week follow up, randomized, multi-center, placebo-controlled
- A Long-Term Extension Study to Evaluate the Safety of Filgotinib in subjects with Ulcerative Colitis
- Combined Phase 2b/3. Double-Blind, Randomized, Placebo-Controlled Studies Evaluating the Efficacy an
- Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT)
- A Phase 2 double blinded, randomised, placebo controlled dose-finding study to evaluate the safety t
- Beta-blocker Stratification using quantitative MRI techniques to assess portal pressure and Response
- A Phase 2b, randomised, double blind, placebo controlled, parallel-group, multicentre protocol to ev
- A prospective randomized multicentre study comparing endoscopic pneumatic balloon dilation and per o
- Reclassifying Constipation Using Magnetic Resonance Imaging Combined With High Resolution Manometry:
- A new MR-based Perianal Crohn’s disease activity score: A multi-centre study (The MAP study)
- A Phase 3, long-term active treatment extension study of mongersen (GED-0301) in subjects with Crohn
- NASH meal response study: The Study of Genetic Factors Involved in Post-Prandial Fat Processing and
- A randomised double-blind controlled phase III study to compare the efficacy and safety of intraveno
- The effect of oral feeding on gastric emptying, small bowel water content, superior mesenteric arter
- A phase I, randomised, double-blind, placebo-controlled, multi-centre, ascending-dose trial to evalu
- A Phase 3, double blind, Randomised, Long-Term, Placebo Controlled, Multicentre study Evaluating the
- The accuracy and acceptability of magnet assisted capsule endoscopy in the diagnosis of oesophageal
- Characterisation of the structural changes associated with small bowel Permeability using MRI in Hea
- The accuracy and acceptibility of magnet assisted capsule endoscopy in the diagnosis of oesophageal
- Pro-Euro-DILI Registry: Creation of a multicentre and multidisciplinary European registry of prospec
- Effect of physical form of apples on gastrointestinal function and satiety: a MRI study (APPLE Study
- A Randomised, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of Topical Alicafors
- Muscle physiology & function in Crohn’s disease and non-alcoholic liver disease
- A pilot randomised controlled trial of the effect of a diet low in poorly digested carbohydrates on
- Case-control Study Evaluating the Genetic Factors Associated with the Development of Non-alcoholic S
- Poorly absorbed carbohydrates (PAC): A case control study between Irritable Bowel Syndrome patients
- A single arm, two-stage, multi-centre, phase II clinical trial investigating the safety and activity
- Assessing Nutrition Through Observation (ANTO Study)
- Evaluation of antibodies to tumor associated antigens as a diagnostic test for hepatocellular carcin
- Reduced intestinal motility in inflammatory Crohn’s Disease optimisation studies on healthy voluntee
- A pilot study to assess the efficancy of intravenous iron isomaltoside 1000 monofer in the managemen
- Magnetic resonance spectroscopy (MRS) Estimation of Glutathione flux in the Liver (MEGL)
- Eating behaviour in Crohn’s disease
- MRI assessment in newly diagnosed coeliac disease and following gluten-free diet treatment (MARCO)
- Reduced Intestinal Motility in Inflammatory Crohn’s Disease (MIC 2)
- Prognostic Biomarkers in HCV Cirrhosis
- Development of quantitative MRI measures for the preliminary assessment and characterization of the
- Optimisation of MRI for use with PEG Electrolyte Challenge Drink for stimulating and observing colon
- The GEM Project: A Multidisciplinary Study on the Genetic, Environmental and Microbial Interactions
- Nottingham Digestive Diseases Biomedical Research Unit Research Tissue Bank
- Exercise therapy to treat abnormalities in appetite and food intake in active Crohn’s disease (Exerc
- Randomised evaluation of algorithm for Crohn’s treatment - Study 2 (REACT 2)
- Altered appetite in Crohn’s disease: The role of the enteroendocrine axis (BROAD)
- A pilot study in healthy volunteers to assess the influence of time spent in the Trendelenburg posi
- Diagnosis of acid reflux disease using novel imaging: A prospective study (NBI NERD)
- A randomised controlled trial of the effect of the low FODMAP diet and dietary oligofructose on gast
- A pilot double blind, randomised, placebo controlled trial of the effect of a diet low in poorly dig
- Evaluation of interventions designed to increase diagnosis and treatment of patients with hepatitis
- Endoscopic trimodal imaging vs. chromoendoscopy as surveillance strategy for neoplasia in ulcerative
- Evaluation of the role of AST:ALT ratio, ELF markers and fibroscan in the detection of methotrexate
- HCV Research UK MRI Study
- Evaluation of the diagnostic accuracy of the Controlled Attenuation Parameter (CAP) measured by Fibr
- Validation of Magnetic Resonance Imaging to characterise gastrointestinal physiology, gut luminal co
- Assessment of a minimally invasive oesophageal cytology collection system (CE marked) in patients wi
- MRI and Microbiota Analysis in Constipation (MIMIC)
- High intensity training & insulin sensitivity: a tissue specific assessment
- The Effects of Isovolumetric and Isoeffective Infusions of Colloid Versus Crystalloid on Renal Blood
- Trent Study of patients with hepatitis C virus infection (HCV Trent Study)
- An investigation of the prevalence and dynamics of carriage of C. difficile in different IBD outpati
- Drug Induced Liver Injury Cohort in Nottingham (DILICIN)
- Functional Magnetic Resonance Imaging (MRI) in assessing dynamic changes induced by hypercapnia,hype
- An Observational Study of the Role of Antibiotics, Inflammation and Changes in Microbiota in the dev
- A double blind randomised placebo controlled phase III trial in patients with chronic idiopathic con
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Publications
- Entries
- Surgeon. 2020
- Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspi
- Role of Drugs Used for Chronic Disease Management on Susceptibility and Severity of COVID-19: A Larg
- Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Se
- A new tool for estimating liver cancer risk after a hepatitis C virus cure
- MR Measures of Small Bowel Wall T2 Are Associated With Increased Permeability
- High-resolution manometry reveals different effect of polyethylene glycol, bisacodyl, and prucalopri
- Chronic constipation in adults: Contemporary perspectives and clinical challenges. 1: Epidemiology,
- Serosal-exposure sign during colonic endoscopic submucosal dissection of a recurrent polyp in ascend
- Reduced brown adipose tissue-associated skin temperature following cold stimulation in children and
- Processing Apples to Puree or Juice Speeds Gastric Emptying and Reduces Postprandial Intestinal Volu
- A nociresponsive specific area of human somatosensory cortex within BA3a: BA3c?
- Measurement of fasted state gastric antral motility before and after a standard bioavailability and
- In Silico Food-Drug Interaction: A Case Study of Eluxadoline and Fatty Meal
- In Severe Alcoholic Hepatitis, Serum Keratin-18 Fragments Are Diagnostic, Prognostic, and Theragnost
- Impact of acute exercise on immediate and following early post-exercise FGF-21 concentration in adul
- Genetic Risk Factors in Drug-Induced Liver Injury Due to Isoniazid-Containing Antituberculosis Drug
- The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver dise
- A critical review of the available evidence on the diagnosis and clinical features of CPPD: do we re
- Acceptability of chronic liver disease screening in a UK primary care setting: a qualitative evaluat
- Seated anorectal manometry during simulated evacuation: A physiologic exercise or a new clinically u
- The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have disti
- Long-term health-related quality of life following colorectal cancer surgery: patient-reported outco
- Late diagnosis of chronic liver disease in a community cohort (UK biobank): determinants and impact
- An international multidisciplinary consensus statement on the prevention of opioid-related harm in a
- Impact of Deoxycholic Acid on Oesophageal Adenocarcinoma Invasion: Effect on Matrix Metalloproteinas
- HLA associations with infliximab-induced liver injury
- Hippocampal functional connectivity in Alzheimer’s disease: a resting state 7T fMRI study
- Erratum to: ‘Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in inje
- Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells
- COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal c
- Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessm
- All Surfaces Are Not Equal in Contact Transmission of SARS-CoV-2
- An organ-sparing approach: endoscopic submucosal hydrodissection followed by appendectomy to remove
- Editorial: treating hepatorenal syndrome-a window and the views
- The provision of nutritional advice and care for cancer patients: a UK national survey of healthcare
- Polygenic architecture informs potential vulnerability to drug-induced liver injury
- Impact Of Direct Acting Antiviral Agents On Liver Function In Patients With Chronic Hepatitis C Viru
- Enterovirus subtyping in a routine UK laboratory setting between 2013 and 2017
- Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo,
- Comparison of the reverse bevel versus Franseen type endoscopic ultrasound needle
- Experiences of using vedolizumab in the treatment of inflammatory bowel disease in the east Midlands
- Feasibility Study of a New Magnetic Resonance Imaging Mini-capsule Device to Measure Whole Gut Trans
- The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorecta
- Processing Apples to Puree or Juice Speeds Gastric Emptying and Reduces Postprandial Intestinal Volu
- Risk factors for serious adverse events associated with multiband mucosectomy in Barrett’s esophagus
- The MRI colonic function test: Reproducibility of the Macrogol stimulus challenge
- Patient-Specific Stress-Abdominal Pain Interaction in Irritable Bowel Syndrome: An Exploratory Exper
- Dynamic Colon Model (DCM): A Cine-MRI Informed Biorelevant In Vitro Model of the Human Proximal Larg
- Feasibility and learning curve of unsupervised colorectal endoscopic submucosal hydrodissection at a
- Prediction of Survival Among Patients Receiving Transarterial Chemoembolization for Hepatocellular C
- Incidence, prevalence and mortality of autoimmune hepatitis in England 1997-2015. A population-based
- Non-invasive risk scores do not reliably identify future cirrhosis or hepatocellular carcinoma in Ty
- Genome-wide Association Study for Alcohol-related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPU
- Gastric emptying: a dog’s dinner
- Editorial: how widespread and serious is non-alcoholic fatty liver disease in the real world?
- Aneuploidy in targeted endoscopic biopsies outperforms other tissue biomarkers in the prediction of
- Risk of hepatocellular carcinoma in Danish outpatients with alcohol-related cirrhosis
- Practice pattern variability in the management of acute severe colitis: a UK provider survey
- Postprandial changes in gastrointestinal function and transit in cystic fibrosis assessed by Magneti
- Post-discharge oral nutritional supplementation after surgery for gastrointestinal cancer: Real or m
- Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic
- Nanopore sequencing from extraction-free direct PCR of dried serum spots for portable hepatitis B vi
- Mortality After Extrahepatic Gastrointestinal and Abdominal Wall Surgery in Patients With Alcoholic
- The impact of high-intensity interval training on inflammatory markers in metabolic disorders: A met
- Use of rapid reading software to reduce capsule endoscopy reading times while maintaining accuracy
- How do people in prison feel about opt-out hepatitis C virus testing?
- Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma
- Pro-adrenomedullin in acute decompensation of liver cirrhosis: relationship with acute-on-chronic li
- Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut
- Will the COVID-19 pandemic affect HCV disease burden?
- Human Bocavirus infection and respiratory tract disease identified in a UK patient cohort
- Tumor-associated autoantibodies in combination with alpha-fetoprotein for detection of early stage h
- Traction is most important for the widespread use of endoscopic submucosal dissection, especially in
- The haemodynamics of the human placenta in utero
- GP access to FIT increases the proportion of colorectal cancers detected on urgent pathways in sympt
- A Gold Standard, CRISPR/Cas9-Based Complementation Strategy Reliant on 24 Nucleotide Bookmark Sequen
- Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-c
- FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steato
- Efficacy of insulin targeted gene therapy for type 1 diabetes mellitus: A systematic review and meta
- The effects of metformin administration on liver enzymes and body composition in non-diabetic patien
- Development and validation of a recommended checklist for assessment of surgical videos quality: the
- Clinical performance of Determine HBsAg 2 rapid test for Hepatitis B detection
- Perioperative nutrition: Recommendations from the ESPEN expert group
- HLA-B 14:01 and HLA-B 35:01 are associated with trimethoprim-sulfamethoxazole induced liver injury
- Accurate non-invasive diagnosis and staging of non-alcoholic fatty liver disease using the urinary s
- Regional differences in human biliary tissues and corresponding in vitro derived organoids
- Response to the comment on: “The Impact of Preoperative Immune-Modulating Nutrition on Outcomes in P
- Population-Based PBPK Model for the Prediction of Time-Variant Bile Salt Disposition within GI Lumin
- Food insecurity and mental health: a systematic review and meta-analysis
- Feasibility and learning curve of unsupervised colorectal endoscopic submucosal hydrodissection at a
- Manometric demonstration of duodenal/jejunal motor function consistent with the duodenal brake mecha
- ESPEN guideline on clinical nutrition in acute and chronic pancreatitis
- Investigation of Oxidative Stress-Related Candidate Genes as Risk Factors for Drug-Induced Liver Inj
- Novel approach to endoscopic submucosal dissection of a cecal lesion with nonlifting sign by submuco
- Endoscopic management of eosinophilic esophagitis presenting as a double lumen esophagus
- The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorecta
- Cost effectiveness of an intervention to increase uptake of hepatitis C virus testing and treatment
- Increasing uptake of hepatitis C virus infection case-finding, testing, and treatment in primary ca
- The management and long-term outcomes of endoscopic and surgical treatment of early esophageal adeno
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