Gastrointestinal & Liver Disorders

Gut Imaging for Function & Transit in Cystic Fibrosis

5th August 2019

Body: Cystic Fibrosis Foundation Therapeutics

Amount: £107,940

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dr-giles-major1 Dr Giles Major

Fighting the Fatty Liver Pandemic

5th August 2019

Body: Research England Institutional Global Challenge Research Fund

Amount: £248,321

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dr-giles-major1 Dr Giles Major

Translational Safety Biomarker Pipeline

5th August 2019

Body: IMI2 (Horizon 2020)

Amount: €28M

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dr-giles-major1 Dr Giles Major

Low Anterior Resection Syndrome (LARS) After Rectal Cancer Treatment

5th August 2019

Body: NIHR RfPB

Amount: £349,884

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dr-giles-major1 Dr Giles Major

A novel and potent antibiotic for treating Clostridium difficile

5th August 2019

Body: MRC DPFS

Amount: £1.7m

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dr-giles-major1 Dr Giles Major

MAGIC2

5th August 2019

Body: NIHR i4i

Amount: £1,224,841

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dr-giles-major1 Dr Giles Major

New insights into digestive function in Cystic Fibrosis using MRI

30th November 2018

Body: NIHR Nottingham BRC Innovation funding initiative

Amount: £15,860

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dr-giles-major1 Dr Giles Major

A new MRI based disease measure in Ulcerative Colitis – Optimisation studies in Healthy Volunteers

1st January 2018

Body: NIHR Nottingham BRC Innovation Fund

Amount: £4,500

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dr-giles-major1 Dr Giles Major

Effect of kiwifruit on Gastrointestinal Fluid Distribution and tansit in Healthy volunteers

1st March 2017

Body: Zespri Group Ltd

Amount: £249,566

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dr-giles-major1 Dr Giles Major

Metagenomic analysis of the Gut Microbiota of the Pre-industrialised Indian Korku Tribe: Prospects for Novel Antimicrobial Discovery

16th January 2017

Body: Faculty of Medicine and Health Sciences Research Board Publication Booster Scheme

Amount: £9,881

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dr-giles-major1 Dr Giles Major

Antimicrobial peptide human deensin-5 and agent for tackling AMR and Crohns disease

1st January 2017

Body: Bridging the gaps award EPSRC University of Nottingham

Amount: £15,653

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dr-giles-major1 Dr Giles Major

Understanding the role of microbial metabolites in the initiation and progression of Crohn’s disease

1st January 2017

Body: BBSRC Industrial Case (iCASE) PhD studentship

Amount: £18,417

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dr-giles-major1 Dr Giles Major

Functional characteristics of a rare MTTP mutation

1st January 2017

Body: The University of Nottingham

Amount: £9,850

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dr-giles-major1 Dr Giles Major

Towards Personalised Therapies for Crohn’s Disease Using Primary Intestinal Enteroids

1st January 2017

Body: Welcome Trust

Amount: £99,051

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dr-giles-major1 Dr Giles Major

A new MR-based Perianal Crohn’s disease activity score: A multi-centre study. The MAP study

24th November 2016

Body: Medical Research Council

Amount: £77,439

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dr-giles-major1 Dr Giles Major

Validation of the Genedrive for HCV RNA testing

1st November 2016

Body: Epistem

Amount: £53,576.00

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dr-giles-major1 Dr Giles Major

VacA mediated immunomodulation

5th April 2016

Body: MRC

Amount: £285,060

​01/10/16 - 01/09/20

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dr-giles-major1 Dr Giles Major

Helicobacter pylori - cellular immunity and protection against multiple sclerosis

5th April 2016

Body: MRC IMPACT DTP Studentship

Amount: £81,932

​01/10/16 - 01/03/2020

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dr-giles-major1 Dr Giles Major

Small bowel motility quantified by cine MRI as a predictor of long term response in patients with Crohn’s disease commencing biological therapy

5th April 2016

Body: EME/NIHR/MRC

Amount: £932,139

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dr-giles-major1 Dr Giles Major

Proof of Concept: Assessment of a Polymer-based Nanoparticulate System to Enhance Drug Delivery of Lactoferrin to Prevent C. difficile Infection

16th March 2016

Body: EPSRC Funding the Gaps Award

Amount: £14,808

01/04/2016 - 01/08/2016

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dr-giles-major1 Dr Giles Major

Assessing the efficacy of liposomal antibiotic formulations for site-specific gastric therapy against Helicobacter pylori infection

1st February 2016

Body: University of Nottingham Pump Priming Award, Antimicrobial Resistance Research Priority Area

Amount: £23,639

01/02/16 - 31/07/16

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dr-giles-major1 Dr Giles Major

The causes of constipation. Reclassifying constipation using MRI and high resolution manometry to define mechanism of disease and target treatment

1st February 2016

Body: MRC experimental medicine challenge

Amount: £1,600,000

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dr-giles-major1 Dr Giles Major

A Microarray Assay for Patient Stratification and Management of C. difficile Infection

1st February 2016

Body: Hermes Fellowship, University of Nottingham

Amount: £24,000

01/02/2016 - 31/07/2016

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dr-giles-major1 Dr Giles Major

Assessment of gut transit in paediatric constipation without ionizing radiation: Magnetic Resonance Imaging transit mini- capsules and methods

1st October 2015

Body: NIHR

Amount: £356,796

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dr-giles-major1 Dr Giles Major

An assessment of muscle function in Crohn's Disease

1st October 2015

Body: Nottingham University Hospitals Charity

Amount: £10,000

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dr-giles-major1 Dr Giles Major

Deconstructing the gut-brain axis in adult Crohn’s disease using fMRI methodology.

1st October 2015

Body: MRC

Amount: £84,258

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dr-giles-major1 Dr Giles Major

Prospective European Drug-Induced Liver Injury Registry (Pro-Euro-DILI Registry)

30th September 2015

Body: European Association for the study of the Liver

Amount: 50’000 €

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dr-giles-major1 Dr Giles Major

Non-invasive detection, stratification and treatment of chronic liver disease in vulnerable elderly adults in the community

1st September 2015

Body: Dunhill Medical Trust

Amount: £134,746

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dr-giles-major1 Dr Giles Major

Nottingham Molecular Pathology Node (NMPN)

1st September 2015

Body: MRC/EPSRC

Amount: £2,400,000

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dr-giles-major1 Dr Giles Major

The Trent HCV Cohort study

21st August 2015

Body: MRC foundation

Amount: £400,000

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dr-giles-major1 Dr Giles Major

Characterising IBS subtypes and their response to stress using MRI

21st August 2015

Body: MRC

Amount: £250,000

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dr-giles-major1 Dr Giles Major

Trent study of patients with Hep-C virus (HCV) infection: Non-invasive assessment of progression of liver disease & cognition in chronic Hep C infection

21st August 2015

Body: Pfizer

Amount: £467,121

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dr-giles-major1 Dr Giles Major

FSF award gastrointestinal response to stress in IBS

21st August 2015

Body: FSf Award

Amount: £150,000

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dr-giles-major1 Dr Giles Major

Evaluation of a non-endoscopic Immunocytological Device (Cytosponge) for Barrett’s Esophagus Screening

21st August 2015

Body: CRUK

Amount: £97,146

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dr-giles-major1 Dr Giles Major

Mode of action of Moviprep: impact on distribution of intestinal fluid and colonic microbiota

21st August 2015

Body: Norgine

Amount: £156,367

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dr-giles-major1 Dr Giles Major

Modelling chemotherapy associated steatohepatitis (CASH) in a microfluidic primary human liver culture system

21st August 2015

Body: NUH Charity

Amount: £9,920

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dr-giles-major1 Dr Giles Major

Drug-Induced Liver Injury

21st August 2015

Body: International SAE Consortium

Amount: £78,327

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dr-giles-major1 Dr Giles Major

NIHR Senior Investigator FSF Award

21st August 2015

Body: NIHR

Amount: £60,000

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dr-giles-major1 Dr Giles Major

Efficacy & mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D)

21st August 2015

Body: EME

Amount: £725,000

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dr-giles-major1 Dr Giles Major

NIA Fellowship - The scarred liver project

1st August 2015

Body: NHS England

Amount: £50,000

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dr-giles-major1 Dr Giles Major

Apply and Develop MRI techniques to characterize the changes in the small bowel associated with permeability in normal and positive control conditions in Healthy Volunteers

1st August 2015

Body: Nottingham Hospitals Charity

Amount: £10,000

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dr-giles-major1 Dr Giles Major

Altered Appetite in Crohn’s disease: Deconstructing the enteroendocrine axis using fMRI.

1st June 2015

Body: BROAD Medical Research Program, USA

Amount: £140,508.32

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dr-giles-major1 Dr Giles Major

Prophylaxis of Clostridium difficile infections

1st April 2015

Body: NIH

Amount: £176,237.38

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dr-giles-major1 Dr Giles Major

Royal Society Wolfson merit award

1st February 2015

Body: Royal Society

Amount: £25,000.00

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dr-giles-major1 Dr Giles Major

Asseel Khalaf PGR studentship

1st January 2015

Body: Kuwait university

Amount: £100,000

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dr-giles-major1 Dr Giles Major

Real world outcomes of treatment of HCV-infected patients based on the use of sofosbuvir

1st January 2015

Body: Gildead Sciences Investigator-led study

Amount: £116,000

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dr-giles-major1 Dr Giles Major

Developing methods for measuring gut permeability and fat infiltration with MRI

1st January 2015

Body: MRC DTP Studentship

Amount: £84,258

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dr-giles-major1 Dr Giles Major

Gut Motility in Crohn’s disease. PhD Studentship

1st January 2015

Body: Ministry of Education, Kuwait

Amount: £100,000

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dr-giles-major1 Dr Giles Major

IBD Educational Grant

1st January 2015

Body: Ferring Pharmaceuticals, Abbvie, MSD

Amount: £8,400

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dr-giles-major1 Dr Giles Major

Pilot study to characterise the skeletal muscle metabolic response to a meal in patients with Crohn’s disease

1st January 2015

Body: School of Life Sciences Research Award, UoN

Amount: £4,500

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dr-giles-major1 Dr Giles Major

Reduced intestinal motility in inflammatory Crohn’s disease – Optimisation studies in healthy volunteers

1st January 2015

Body: NUH Charity

Amount: £10,000

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dr-giles-major1 Dr Giles Major

Phenotypic assessment of C. difficile mutants in a human in vitro model of C. difficile infection

1st January 2015

Body: University of Nottingham School of Life Sciences Small Grants Funding Scheme

Amount: £4,500

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dr-giles-major1 Dr Giles Major

Assessment of the in vivo effects of a glycosylated dendrimer, PETIM-DG, in a murine model of C. difficile infection

1st January 2015

Body: University of Nottingham FRB IRIC Funding Scheme

Amount: £7,000

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dr-giles-major1 Dr Giles Major

CLOSPORE: Understanding the Clostridium Spore, a Prerequiste for Disease Interventions and Exploitation

1st January 2015

Body: MARIE SKLODOWSKA-CURIE ACTION ITN.

Amount: £2,865,288.79

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dr-giles-major1 Dr Giles Major

Diagnosis of Acid Reflux Disease

1st October 2014

Body: AstraZeneca

Amount: £132,300

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dr-giles-major1 Dr Giles Major

A Prospective Study on a Relationship Between Hydr

1st October 2014

Body: European Hydration institute

Amount: £61,843

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dr-giles-major1 Dr Giles Major

Stratifying risk of gastric adenocarcinoma in Helicobacter pylori infected patients: development of a non-invasive test

1st October 2014

Body: NUH Charities Pump Priming Award

Amount: £5,892

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dr-giles-major1 Dr Giles Major

Katie Elisabeth Rollins ESPEN Research Fellowship

1st August 2014

Body: European Society for Clinical Nutrition and metabolism

Amount: £40,408

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dr-giles-major1 Dr Giles Major

Confidence in Concept 2013

1st August 2014

Body: MRC

Amount: £85,612

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dr-giles-major1 Dr Giles Major

MRI Study

1st July 2014

Body: Braun

Amount: £97,000

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dr-giles-major1 Dr Giles Major

MagniView Study

1st July 2014

Body: Pentax Europe

Amount: £7,912

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dr-giles-major1 Dr Giles Major

Effect of Gluten content of bread

1st June 2014

Body: NUH Charity

Amount: £9,492

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dr-giles-major1 Dr Giles Major

EASL registry Grant

1st June 2014

Body: EASL

Amount: £35,798.33

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dr-giles-major1 Dr Giles Major

Helicobacter Eradication vs Aspirin Toxicity

1st June 2014

Body: NIHR

Amount: £1,819,174

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dr-giles-major1 Dr Giles Major

The effect of extreme Trendelenburg positioning

1st June 2014

Body: European Association for Endoscopic Surgery

Amount: £39,222.45

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dr-giles-major1 Dr Giles Major

Dietary evaluation and interventions in NAFLD in south indian community

1st April 2014

Body: BSG

Amount: £9,904

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dr-giles-major1 Dr Giles Major

Evaluation of Interventions designed to increase diagnosis and treatment of patients with HCV infect

1st January 2014

Body: Department of Health Policy

Amount: £1,112,000

Evaluation of Interventions designed to increase diagnosis and treatment of patients with HCV infection

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dr-giles-major1 Dr Giles Major

Quantitative Magnetic Resonance Imaging (MRI) Techniques in the evaluation and estimation of portal

1st January 2014

Body: CORE

Amount: £21,600

Quantitative Magnetic Resonance Imaging (MRI) Techniques in the evaluation and estimation of portal hypertension

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dr-giles-major1 Dr Giles Major

Stratifying risk of gastric adenocarcinoma in Helicobacter pylori infected patients: development of a non-invasive test

1st January 2014

Body: NUH Charity

Amount: £5,892

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dr-giles-major1 Dr Giles Major

Scarred Liver Project

1st January 2014

Body: East Midlands Academic Health Science Network

Amount: £491,000

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dr-giles-major1 Dr Giles Major

Pump Priming study

1st January 2014

Body: NUH Charity

Amount: £10,000

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dr-giles-major1 Dr Giles Major

European Association for Endoscopic Surgery and other interventional techniques

1st January 2014

Body: European Association for Endoscopic Surgery (EAES)

Amount: £36,633.22

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dr-giles-major1 Dr Giles Major

MRC fellowship

1st October 2013

Body: MRC

Amount: £194,730

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dr-giles-major1 Dr Giles Major

CIC Assessing chronic liver injury using dynamic MRI

1st October 2013

Body: MRC

Amount: £69,597

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dr-giles-major1 Dr Giles Major

Towards the treatment of C Diff

1st October 2013

Body: MRC

Amount: £109,400.00

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dr-giles-major1 Dr Giles Major

Stratified Medicine to optimise Treatment for HCV infection

1st September 2013

Body: MRC

Amount: £5,200,000

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dr-giles-major1 Dr Giles Major

Faecal Incontinence: Is there evidence for Synergy

1st September 2013

Body: Norgine

Amount: £50,000

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dr-giles-major1 Dr Giles Major

ALL-HEART Allopurinol and cardiovascular outcome

1st September 2013

Body: NIHR

Amount: £274,121

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dr-giles-major1 Dr Giles Major

Variety of Beverages Increase Fluid Consumption

1st August 2013

Body: NUH pump priming

Amount: £12,000

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dr-giles-major1 Dr Giles Major

Focus groups NAFLD patients

1st August 2013

Body: NUH Charity

Amount: £10,110

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dr-giles-major1 Dr Giles Major

Olympus-Core National Endoscopy Fellowship

1st July 2013

Body: Olympus-core

Amount: £180,000

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dr-giles-major1 Dr Giles Major

Telomere Length and Telomerase Activity

1st June 2013

Body: NUH Charity

Amount: £8,260

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dr-giles-major1 Dr Giles Major

Acellular approaches to therapeutic delivery

1st January 2013

Body: MRC

Amount: £4,600,000

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dr-giles-major1 Dr Giles Major

Barretts oesophagus related neoplasia

1st January 2013

Body: UEG

Amount: £71,686.17

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dr-giles-major1 Dr Giles Major

L171 Vaper

1st December 2012

Body: United Lincolnshire Hospitals NHS Trust

Amount: £18,083

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dr-giles-major1 Dr Giles Major

11GA001 Controlled Trial of “Follow On” Rifaximin

1st December 2012

Body: RFPB

Amount: £111,568.00

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dr-giles-major1 Dr Giles Major

Mr Krishna Kumar Varadhan-ESPEN Fellowship

1st August 2012

Body: European Society for Clinical Nutrition and metabolism

Amount: £23,939

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dr-giles-major1 Dr Giles Major

The Assessment of Liver Fibrogenesis

1st May 2012

Body: Conatus

Amount: £61,983

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dr-giles-major1 Dr Giles Major

The aetiology of pain in chronic pancreatitis

1st April 2012

Body: NUH pump priming

Amount: £9,825

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dr-giles-major1 Dr Giles Major

Oesophageal and Gastric Varices in Cirrhosis

1st December 2011

Body: Intromedic

Amount: £50,000

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dr-giles-major1 Dr Giles Major

Clostridium research project

1st December 2011

Body: Evonik Industries AG

Amount: £180,000.00

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dr-giles-major1 Dr Giles Major

FAST (PROBE)

1st October 2011

Body: A Menarini Industrie Farmaceutiche

Amount: £335,563

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dr-giles-major1 Dr Giles Major

Nilanjana tewari CORE fellowship

1st August 2011

Body: CORE

Amount: £179,665

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dr-giles-major1 Dr Giles Major

Establishment of a resource for Long-Term study of hepatitis C Virus infection in the UK - HCV Resea

1st May 2011

Body: MRC

Amount: £1,920,000

Establishment of a resource for Long-Term study of hepatitis C Virus infection in the UK - HCV Research UK

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dr-giles-major1 Dr Giles Major

Study to assess safety of GSK1605786A

1st April 2011

Body: GlaxoSmithKline

Amount: £4,401

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dr-giles-major1 Dr Giles Major

Subjects with moderately to severely active crohns

1st February 2011

Body: GlaxoSmithKline

Amount: £3,126

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dr-giles-major1 Dr Giles Major

In vivo imaging of T-cell migration in Helicobacter pylori infection

1st October 2010

Body: MRC Strategic Skills Award

Amount: £15,000

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dr-giles-major1 Dr Giles Major

FSF Award Gastrointestinal response to stress in IBS

1st September 2010

Body: Nottingham University Hospitals NHS trust

Amount: £150,000

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dr-giles-major1 Dr Giles Major

Standard Care Versus Celecoxib Outcome study

1st June 2010

Body: Pfizer

Amount: £285,599

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dr-giles-major1 Dr Giles Major

Helicobacter pylori duodenal ulcer promoting gene A

1st January 2010

Body: MRC Clinical Training Fellowship

Amount: £183,201

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dr-giles-major1 Dr Giles Major